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Studies designed to provide insight into clinical practice in the real world are called pragmatic trials. They are typically characterized by a focus on practical aspects of the research design, like the recruitment process and consent, adherence, and the use of commonly available equipment.

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Pragmatic, a software company provides a variety of casino games for online gambling platforms. Its iGaming software is used by the top operators as well as casinos that are located in the land. The company offers front-end tools for design, analysis, marketing, promotions and payment systems, as well as security, customer service, and bug reporting. The company also provides security, high-quality graphics, gaming and security.

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A pragmatic trial that uses different investigators and participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This type of heterogeneity which is vital for pragmatic trials to be valid and 프라그마틱 공식홈페이지 to reduce bias in the results is also essential. A high degree of heterogeneity, however can result in problems with the design of the trial.

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The purpose of pragmatic trials is to simulate real-life scenarios and gain maximum validity externally. They are usually requested by policy makers and practitioners to aid in their decision-making. They can be used to determine the cause-effect relationship of an intervention with its outcomes. They should not, however be used to replace the need for explanation studies.

The pragmatism idea is controversial, and there are questions about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which confirm the validity of a clinical or physiological hypothesis as well as pragmatic trials, which guide the practice and policy decisions. They also suggested an approach to pragmatic trials, which they called PRECIS.2 This tool was designed to define the features of a pragmatic trial which includes the recruitment process, the design and implementation of the intervention, and the follow-up.

The number of pragmatic trials is increasing. A recent Medline search using the keywords naturalistic and pragmatic, which was limited to controlled trials that are randomized (RCTs) produced 34 articles, which are shown in red in Figure 2. This indicates that the health sciences community has become more aware of the importance of pragmatism. It is important to keep in mind, however, that the majority of studies were conducted in primary-care settings.